ISUZU Medium Duty Trucks For Sale

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    About Isuzu

    Isuzu manufactures Class 3 through Class 5 gas-powered and Class 4 through Class 7 diesel-powered trucks with a low-cab forward (LCF) design that the manufacturer says provides greater maneuverability, especially in urban settings.

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    1 - 28 of 2,965 Listings

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    Mileage60,882 mi
    VINJALC4W163P7013543
    Location: Wausau, Wisconsin
    Seller: Nina Dittmar
    Mileage136,281 mi
    Body Length16 ft
    Location: Pompano Beach, Florida
    Seller: TLC Truck and Equipment
    Mileage104,091 mi
    Length71 ft
    Location: Chattanooga, Tennessee
    Mileage218,188 mi
    Engine ManufacturerISUZU
    Location: Jacksonville, Florida
    Seller: Hunger Fight
    Mileage149,000 mi
    Engine ManufacturerGMC
    Location: Pleasant Valley, Missouri
    Seller: JDog Junk Removal & Hauling KC
    Mileage183,963 mi
    ReeferThermo King
    Location: Jacksonville, Florida
    Seller: Beacon Fisheries
    Mileage188,000 mi
    Engine ManufacturerISUZU
    Location: Woodleaf, North Carolina
    Seller: Matthew Peachey
    Mileage146,900 mi
    Horsepower300 HP
    Location: Jeannette, Pennsylvania
    Seller: Frank Fletcher
    Mileage149,847 mi
    Body Length14 ft
    Location: Green Bay, Wisconsin
    Seller: PACKER CITY INTL
    Mileage134,607 mi
    Location: Las Vegas, Nevada
    Seller: Jeffrey Thorn
    Mileage358,136 mi
    VINJALC4W161B7000153
    Location: Los Angeles, California
    Seller: Yousef Lalezari
    Mileage176,777 mi
    Bed Length16 ft
    Location: Sacramento, California
    Seller: Kurt Teitscheid
    Mileage3,828 mi
    Engine ManufacturerISUZU
    Location: Palm Beach Gardens, Florida
    Seller: Junk-it Tampa
    Mileage200 mi
    Length14 ft
    Location: Marietta, Ga, Georgia
    Seller: Concrete Line Pump
    Mileage33,924 mi
    Body Length20 ft
    Location: Worcester, Massachusetts
    Seller: H.T. Services Inc.
    Mileage54,248 mi
    Engine ManufacturerGM
    Location: Uppr Chichstr, Pennsylvania
    Seller: J&K Trash
    Location: Atlanta, Georgia
    Seller: Eric Reynolds
    Mileage218,711 mi
    Engine ManufacturerISUZU
    Location: Sicily Island, Louisiana
    Seller: Zerick Dunbar
    Mileage136,328 mi
    Engine ManufacturerISUZU
    Location: Fort Myers, Florida
    Seller: Diane Bello
    Mileage230,882 mi
    Engine ManufacturerISUZU
    Location: Fort Myers, Florida
    Seller: Diane Bello
    Mileage274,877 mi
    Engine ManufacturerISUZU
    Location: Broadview, Illinois
    Seller: Ed Buchta
    On-Site Auction
     
     
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    Auction Date:9/19/2026 8:00:00 AM (CDT)
    VINJALE5W168G7301340
    Location: Callahan, Florida
    Seller: Weeks Auction Company
    Mileage166,004 mi
    VIN54DK6S160LSG70211
    Location: Sacramento, California
    Seller: Housby Truck & Equipment Solutions
    Mileage95,470 mi
    Body Length16 ft
    Location: Miami, Florida
    Seller: Truck and Van Outlet
    Mileage82,844 mi
    Body Length16 ft
    Location: Pittsburgh, Pennsylvania
    Mileage114,481 mi
    Engine ManufacturerISUZU
    Location: Los Angeles, California
    Seller: TCI COMMERCE (LA)
    Mileage69,000 mi
    DoorsRoll up
    Location: Charlotte, North Carolina
    Seller: AMERITRUCK LLC
    Mileage107,542 mi
    Body Length16 ft
    Location: Miami, Florida
    Seller: Truck and Van Outlet

    About Isuzu

    Isuzu Commercial Truck of America is a subsidiary of Isuzu Motors Limited of Japan that manufactures Class 3 through Class 5 gas-powered and Class 4 through Class 7 diesel-powered trucks. The company’s popular N-Series and F-Series models feature a low-cab forward (LCF) design, which Isuzu says provides greater maneuverability, especially in urban settings. Isuzu says it has led the American market in sales of commercial LCF trucks every year since 1986. In 2019, while marking its 35th anniversary in the American market, Isuzu said it had delivered more than half a million trucks in North America, and held a 73% share of the LCF market for Class 3 through Class 5 vehicles. Isuzu entered the U.S. market in 1984 with an 87-horsepower (65-kilowatt) KS22 truck with a no-tilt cab.


    Isuzu NPR-HD

    Isuzu Through The Years

    Isuzu’s history stretches back to 1916, when Tokyo Ishikawajima Shipbuilding and Engineering Co., Ltd. and Tokyo Gas and Electric Industrial Co. began plans for automobile production. In 1919, Isuzu produced Japan’s first automobile, a Wolseley A9 car. The company produced its first air-cooled diesel engine in 1936. In 1959, Isuzu introduced the N-Series of trucks in Japan. It announced its F-Series of trucks in 1970. The first American-built gas-powered NPR truck rolled off the assembly line in 1994. By 2002, cumulative U.S. sales of Isuzu trucks had topped 275,000.

    N-Series Trucks

    Isuzu produces N-Series trucks in Gas, Class 5 Gas, and Diesel lineups. Gas-powered models include the Class 3 NPR and Class 4 NPR-HD, both available in standard or crew cabs. They include 6.6-liter V8 engines rated for 350 horsepower (260 kilowatts) in wheelbases from 109 to 176 inches (2,768 to 4,470 millimeters). Diesel models include the Class 4 NPR-HD and NPR-XD and Class 5 NQR and NRR. They come in standard or crew cab varieties with wheelbases from 109 to 212 in. (5,385 mm), and a new four-wheel disc braking system and Standard Electronic Vehicle Stability Control system. The trucks include 5.2-liter turbocharged, intercooled four-cylinder engines rated for 215 HP (160 kW).

    In 2021, Isuzu began producing Class 5 gas-powered NQR and NRR models with standard or crew cabs and 6.0-liter V8 engines rated for 311 HP (232 kW). Isuzu says the NRR is the industry’s first LCF truck with a 19,500-pound (8,845-kilogram) gross vehicle weight rating (GVWR) to offer a gas option. Both models include a six-speed Allison 1000 RDS transmission with power take-off (PTO), marking the first time Isuzu has offered PTO in a gas-powered truck.

    F-Series Trucks

    Isuzu’s F-Series lineup features Class 6 FTR and FVR Derated variants and the Class 7 FVR, Isuzu’s first F-Series Class 7 offering. All models come with a standard cab, and wheelbases range from 152 to 248 in. (3,860 to 6,299 mm). Customers can equip the trucks with air suspension and a 50- or 100-gallon (189- or 378-liter) fuel tank. The trucks feature a 6.7-liter six-cylinder Cummins B6.7 diesel engine rated for 260 HP (194 kW).

    The latest generation of F-Series trucks is the first to include engines from the Isuzu Cummins Powertrain Partnership that Isuzu and Cummins formed in 2019. The companies have also announced plans to develop a prototype medium-duty, battery-electric truck based on an Isuzu F-Series truck and powered by a Cummins PowerDrive 6000 hybrid powertrain.

    Find Your Next Isuzu Truck

    TruckPaper.com offers new and used Isuzu N- and F-Series trucks for sale in numerous configurations, including beverage, cab-and-chassis, dry-cargo delivery box, dump, landscaping, and reefer box trucks, among others. You’ll frequently find big selections of NPR, NPR-HD, NRR, and NQR models for sale on the site.

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